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Sex-linked diseases are passed down through families through one of the x or y chromosomes. Dominant inheritance occurs when an abnormal gene from one parent causes disease, even though the matching gene from the other parent is normal. Sex linked inheritance definition , traits and example are disscuded in this research article. The inheritance of a trait (phenotype) that is determined by a gene located on one of the sex chromosomes is called sex linked inheritance. Whereas, autosomal inheritance occurs via the genes in autosomes. Both types of inheritance exist as two types recessive and dominant. However, autosomal inheritance occurs in equal frequency in males and females while it affects males and females differently in sex-linked inheritance. The x-linked recessive genes show criss-cross pattern of inheritance. In criss-cross inheritance, an x-linked recessive gene is transmitted from p1 male parent (father) to f2 male progeny (grandsons) through its f1 heterozygous females (daughters), which are called carriers) and different f1 and f2 results (ratios) in the reciprocal crosses. Human genetic disease - human genetic disease - sex-linked inheritance in humans, there are hundreds of genes located on the x chromosome that have no counterpart on the y chromosome. The traits governed by these genes thus show sex-linked inheritance. This type of inheritance has certain unique characteristics, which include the following (1) there is no male-to-male (father-to-son.). Females possessing one x-linked recessive mutation are considered carriers and will generally not manifest clinical symptoms of the disorder, although differences in x chromosome inactivation can lead to varying degrees of clinical expression in carrier females since some cells will express one x alleleand some will express the other. All males possessing an x-linked recessive mutation will be affected, since males have only a single x chromosome and therefore have only one copy of x-linked genes. These genes are either y-linked if found on the y chromosome or x-linked if found on the x chromosome. Since males only have one x chromosome (xy), in x-linked recessive traits, the phenotype is fully expressed. Sex-linked recessive definition sex-linked diseases are passed down through families through one of the x or y chromosomes. Dominant inheritance occurs when an abnormal gene from one parent causes disease, even though the matching gene from the other parent is normal. The inheritance of sex linked genes or a trait is known as sex linked inheritance. Sex linkage was first discovered by morgan in 1910 in fruit fly, drosophila melanogaster. The fruit fly has xx and xy sex chromosomes in the female and male respectively.

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